- Head of Research Group: Prof. Attila CSIKÁSZ-NAGY
- Members of the Group: Dr. Csaba István PONGOR, Dr. János JUHÁSZ, Tünde Éva GAIZER, Bence Márk KEÖMLEY-HORVÁTH, Marcell MISKI, Bence GAIZER, Valentina MADÁR, Bíborka PILLÉR, János SZALMA, Áron WEBER
- Contact: csikasz-nagy.attila@itk.ppke.hu
- We investigate the spatial and temporal dynamics of molecular and cellular regulatory networks (1) experimentally and (2) through mathematical modelling and model analysis techniques. The main research line on molecular networks focuses on the regulation of cell growth and proliferation, especially dealing with cell cycle regulation and its connec-tion to ageing, to the circadian clock and to spatial control of cell growth.
- We also develop tools to predict changes in the complexome upon perturbations by drugs or disease. On the cellular networks track we investigate cell-cell interactions in yeast colonies and use the results of this approach in combination with theoretical ideas to design and synthetically establish multicellular colonies for specific functions. Additionally, as part of a national consortium we work on models of disease spreading in structured populations.
- More information about the research group
Microscopy image and simulation of the growth of two labelled yeast strains. On the left two strains were fluorescently labelled and grown on YPD solid media. On the right simulation results of an agent-based model, where two differently coloured strains were grown together.